Human STEAP3 activation kit by CRISPRa

CAT#: GA110635

STEAP3 CRISPRa kit - CRISPR gene activation of human STEAP3 metalloreductase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: STEAP3
• Locus ID: 55240
• Kit Components:

  GA110635G1, STEAP3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA110635G2, STEAP3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA110635G3, STEAP3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001008410, NM_018234, NM_138637, NM_182915
• Synonyms: AHMIO2; dudlin-2; dudulin-2; pHyde; STMP3; TSAP6
• Summary: This gene encodes a multipass membrane protein that functions as an iron transporter. The encoded protein can reduce both iron (Fe3+) and copper (Cu2+) cations. This protein may mediate downstream responses to p53, including promoting apoptosis. Deficiency in this gene can cause anemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]