Human Mucolipin 3 (MCOLN3) activation kit by CRISPRa

CAT#: GA110671

MCOLN3 CRISPRa kit - CRISPR gene activation of human mucolipin 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MCOLN3
• Locus ID: 55283
• Kit Components:

  GA110671G1, MCOLN3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA110671G2, MCOLN3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA110671G3, MCOLN3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001253693, NM_018298
• Synonyms: TRP-ML3; TRPML3
• Summary: This gene encodes one of members of the mucolipin cation channel proteins. Mutation studies of the highly similar protein in mice have shown that the protein is found in cochlea hair cells, and mutant mice show early-onset hearing loss and balance problems. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]