Human SAPS3 (PPP6R3) activation kit by CRISPRa

CAT#: GA110679

PPP6R3 CRISPRa kit - CRISPR gene activation of human protein phosphatase 6 regulatory subunit 3


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Find the corresponding CRISPRi Inhibitor Kit

USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol PPP6R3
Locus ID 55291
Kit Components

GA110679G1, PPP6R3 gRNA vector 1 in pCas-Guide-CRISPRa

GA110679G2, PPP6R3 gRNA vector 2 in pCas-Guide-CRISPRa

GA110679G3, PPP6R3 gRNA vector 3 in pCas-Guide-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100058

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001164160, NM_001164161, NM_001164162, NM_001164163, NM_001164164, NM_018312, NM_001352347, NM_001352348, NM_001352349, NM_001352350, NM_001352351, NM_001352352, NM_001352353, NM_001352354, NM_001352355, NM_001352356, NM_001352357, NM_001352358, NM_001352359, NM_001352360, NM_001352361, NM_001352362, NM_001352363, NM_001352364, NM_001352365, NM_001352366, NM_001352367, NM_001352368, NM_001352369, NM_001352370, NM_001352371, NM_001352372, NM_001352373, NM_001352374, NM_001352375, NM_001352376, NM_001352377, NM_001352378, NM_001352379, NM_001352380, NR_147965, NR_147966, NR_147967, NR_147968, NR_147969, NR_147970, NR_147971
Synonyms C11orf23; PP6R3; SAP190; SAPL; SAPLa; SAPS3
Summary Protein phosphatase regulatory subunits, such as SAPS3, modulate the activity of protein phosphatase catalytic subunits by restricting substrate specificity, recruiting substrates, and determining the intracellular localization of the holoenzyme. SAPS3 is a regulatory subunit for the protein phosphatase-6 catalytic subunit (PPP6C; MIM 612725) (Stefansson and Brautigan, 2006 [PubMed 16769727]). [supplied by OMIM, Nov 2010]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.