SAPS3 (PPP6R3) Human Gene Knockout Kit (CRISPR)

CAT#: KN414636

PPP6R3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 linear donor
• Donor DNA: EF1a-GFP-P2A-Puro
• Symbol: PPP6R3
• Locus ID: 55291
• Disclaimer: The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001164160, NM_001164161, NM_001164162, NM_001164163, NM_001164164, NM_018312, NM_001352347, NM_001352348, NM_001352349, NM_001352350, NM_001352351, NM_001352352, NM_001352353, NM_001352354, NM_001352355, NM_001352356, NM_001352357, NM_001352358, NM_001352359, NM_001352360, NM_001352361, NM_001352362, NM_001352363, NM_001352364, NM_001352365, NM_001352366, NM_001352367, NM_001352368, NM_001352369, NM_001352370, NM_001352371, NM_001352372, NM_001352373, NM_001352374, NM_001352375, NM_001352376, NM_001352377, NM_001352378, NM_001352379, NM_001352380, NR_147965, NR_147966, NR_147967, NR_147968, NR_147969, NR_147970, NR_147971
• Synonyms: C11orf23; PP6R3; SAP190; SAPL; SAPLa; SAPS3
• Summary: Protein phosphatase regulatory subunits, such as SAPS3, modulate the activity of protein phosphatase catalytic subunits by restricting substrate specificity, recruiting substrates, and determining the intracellular localization of the holoenzyme. SAPS3 is a regulatory subunit for the protein phosphatase-6 catalytic subunit (PPP6C; MIM 612725) (Stefansson and Brautigan, 2006 [PubMed 16769727]). [supplied by OMIM, Nov 2010]