Human PI4K2A activation kit by CRISPRa

CAT#: GA110736

PI4K2A CRISPRa kit - CRISPR gene activation of human phosphatidylinositol 4-kinase type 2 alpha

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PI4K2A
• Locus ID: 55361
• Kit Components:

  GA110736G1, PI4K2A gRNA vector 1 in pCas-Guide-CRISPRa

  GA110736G2, PI4K2A gRNA vector 2 in pCas-Guide-CRISPRa

  GA110736G3, PI4K2A gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_018425
• Synonyms: PI4KII; PIK42A
• Summary: Phosphatidylinositolpolyphosphates (PtdInsPs) are centrally involved in many biologic processes, ranging from cell growth and organization of the actin cytoskeleton to endo- and exocytosis. PI4KII phosphorylates PtdIns at the D-4 position, an essential step in the biosynthesis of PtdInsPs (Barylko et al., 2001 [PubMed 11244087]). [supplied by OMIM, Mar 2008]