Human SOX6 activation kit by CRISPRa

CAT#: GA110786

SOX6 CRISPRa kit - CRISPR gene activation of human SRY-box transcription factor 6

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SOX6
• Locus ID: 55553
• Kit Components:

  GA110786G1, SOX6 gRNA vector 1 in pCas-Guide-CRISPRa

  GA110786G2, SOX6 gRNA vector 2 in pCas-Guide-CRISPRa

  GA110786G3, SOX6 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001145811, NM_001145819, NM_017508, NM_033326, NM_001367873, NM_001367872
• Synonyms: HSSOX6; SOXD
• Summary: This gene encodes a member of the D subfamily of sex determining region y-related transcription factors that are characterized by a conserved DNA-binding domain termed the high mobility group box and by their ability to bind the minor groove of DNA. The encoded protein is a transcriptional activator that is required for normal development of the central nervous system, chondrogenesis and maintenance of cardiac and skeletal muscle cells. The encoded protein interacts with other family members to cooperatively activate gene expression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009]