Human KIF27 activation kit by CRISPRa

CAT#: GA110801

KIF27 CRISPRa kit - CRISPR gene activation of human kinesin family member 27

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: KIF27
• Locus ID: 55582
• Kit Components:

  GA110801G1, KIF27 gRNA vector 1 in pCas-Guide-CRISPRa

  GA110801G2, KIF27 gRNA vector 2 in pCas-Guide-CRISPRa

  GA110801G3, KIF27 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001271927, NM_001271928, NM_017576, NM_001354069, NM_001354070, NM_001354071
• Summary: This gene is a member of the KIF27 (kinesin 4) sub-family of the mammalian kinesin family. The gene is an ortholog of the Drosophila Cos2 gene, which plays an important role in the Hedgehog signaling pathway. The encoded protein contains an N-terminal motor domain which includes nucleotide-binding and microtubule-interacting regions, a stalk domain containing a predicted coiled coil motif and a C-terminal tail domain. Alternatively spliced transcript variants have been observed for this gene. Pseudogenes associated with this gene are located on chromosome 9. [provided by RefSeq, Dec 2012]