Human TASP1 activation kit by CRISPRa

CAT#: GA110827

TASP1 CRISPRa kit - CRISPR gene activation of human taspase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TASP1
• Locus ID: 55617
• Kit Components:

  GA110827G1, TASP1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA110827G2, TASP1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA110827G3, TASP1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001323602, NM_001323603, NM_001323604, NM_017714, NR_136628, NR_136629, NR_136630, NR_136631
• Synonyms: C20orf13; dJ585I14.2
• Summary: This gene encodes an endopeptidase that cleaves specific substrates following aspartate residues. The encoded protein undergoes posttranslational autoproteolytic processing to generate alpha and beta subunits, which reassemble into the active alpha2-beta2 heterotetramer. It is required to cleave MLL, a protein required for the maintenance of HOX gene expression, and TFIIA, a basal transcription factor. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]