Human TMEM127 activation kit by CRISPRa

CAT#: GA110856

TMEM127 CRISPRa kit - CRISPR gene activation of human transmembrane protein 127

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TMEM127
• Locus ID: 55654
• Kit Components:

  GA110856G1, TMEM127 gRNA vector 1 in pCas-Guide-CRISPRa

  GA110856G2, TMEM127 gRNA vector 2 in pCas-Guide-CRISPRa

  GA110856G3, TMEM127 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001193304, NM_017849, NM_032218
• Synonyms: FLJ20507; FLJ22257
• Summary: This gene encodes a transmembrane protein with 3 predicted transmembrane domains. The protein is associated with a subpopulation of vesicular organelles corresponding to early endosomal structures, with the Golgi, and with lysosomes, and may participate in protein trafficking between these structures. Mutations in this gene and several other genes cause pheochromocytomas. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Aug 2010]