Human C20orf31 (EDEM2) activation kit by CRISPRa

CAT#: GA110928

EDEM2 CRISPRa kit - CRISPR gene activation of human ER degradation enhancing alpha-mannosidase like protein 2


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USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol EDEM2
Locus ID 55741
Kit Components

GA110928G1, EDEM2 gRNA vector 1 in pCas-Guide-CRISPRa

GA110928G2, EDEM2 gRNA vector 2 in pCas-Guide-CRISPRa

GA110928G3, EDEM2 gRNA vector 3 in pCas-Guide-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100058

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001145025, NM_018217, NR_026728
Synonyms bA4204.1; C20orf31; C20orf49
Summary In the endoplasmic reticulum (ER), misfolded proteins are retrotranslocated to the cytosol and degraded by the proteasome in a process known as ER-associated degradation (ERAD). EDEM2 belongs to a family of proteins involved in ERAD of glycoproteins (Mast et al., 2005 [PubMed 15537790]). [supplied by OMIM, Mar 2008]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.