Human C20orf31 (EDEM2) activation kit by CRISPRa
CAT#: GA110928
EDEM2 CRISPRa kit - CRISPR gene activation of human ER degradation enhancing alpha-mannosidase like protein 2
Find the corresponding CRISPRi Inhibitor Kit
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 3gRNAs, 1 scramble ctrl and 1 enhancer vector |
Symbol | EDEM2 |
Locus ID | 55741 |
Kit Components | GA110928G1, EDEM2 gRNA vector 1 in pCas-Guide-CRISPRa GA110928G2, EDEM2 gRNA vector 2 in pCas-Guide-CRISPRa GA110928G3, EDEM2 gRNA vector 3 in pCas-Guide-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100058 |
Disclaimer | The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001145025, NM_018217, NR_026728 |
Synonyms | bA4204.1; C20orf31; C20orf49 |
Summary | In the endoplasmic reticulum (ER), misfolded proteins are retrotranslocated to the cytosol and degraded by the proteasome in a process known as ER-associated degradation (ERAD). EDEM2 belongs to a family of proteins involved in ERAD of glycoproteins (Mast et al., 2005 [PubMed 15537790]). [supplied by OMIM, Mar 2008] |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN400124 | EDEM2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
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