Human CHFR activation kit by CRISPRa

CAT#: GA110930

CHFR CRISPRa kit - CRISPR gene activation of human checkpoint with forkhead and ring finger domains

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CHFR
• Locus ID: 55743
• Kit Components:

  GA110930G1, CHFR gRNA vector 1 in pCas-Guide-CRISPRa

  GA110930G2, CHFR gRNA vector 2 in pCas-Guide-CRISPRa

  GA110930G3, CHFR gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001161344, NM_001161345, NM_001161346, NM_001161347, NM_018223
• Synonyms: RNF116; RNF196
• Summary: This gene encodes an E3 ubiquitin-protein ligase required for the maintenance of the antephase checkpoint that regulates cell cycle entry into mitosis and, therefore, may play a key role in cell cycle progression and tumorigenesis. The encoded protein has an N-terminal forkhead-associated domain, a central RING-finger domain, and a cysteine-rich C-terminal region. Alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq, Mar 2014]