Human EXOC1 activation kit by CRISPRa

CAT#: GA110949

EXOC1 CRISPRa kit - CRISPR gene activation of human exocyst complex component 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: EXOC1
• Locus ID: 55763
• Kit Components:

  GA110949G1, EXOC1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA110949G2, EXOC1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA110949G3, EXOC1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001024924, NM_018261, NM_178237
• Synonyms: BM-102; SEC3; SEC3L1; SEC3P
• Summary: The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]