Human NGLY1 activation kit by CRISPRa

CAT#: GA110953

NGLY1 CRISPRa kit - CRISPR gene activation of human N-glycanase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NGLY1
• Locus ID: 55768
• Kit Components:

  GA110953G1, NGLY1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA110953G2, NGLY1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA110953G3, NGLY1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001145293, NM_001145294, NM_001145295, NM_018297
• Synonyms: CDDG; CDG1V; PNG1; PNGase
• Summary: This gene encodes an enzyme that catalyzes hydrolysis of an N(4)-(acetyl-beta-D-glucosaminyl) asparagine residue to N-acetyl-beta-D-glucosaminylamine and a peptide containing an aspartate residue. The encoded enzyme may play a role in the proteasome-mediated degradation of misfolded glycoproteins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009]