Human LMBRD1 activation kit by CRISPRa

CAT#: GA110970

LMBRD1 CRISPRa kit - CRISPR gene activation of human LMBR1 domain containing 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: LMBRD1
• Locus ID: 55788
• Kit Components:

  GA110970G1, LMBRD1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA110970G2, LMBRD1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA110970G3, LMBRD1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_018368, NM_001363722, NM_001367271, NM_001367272
• Synonyms: C6orf209; LMBD1; MAHCF; NESI
• Summary: This gene encodes a lysosomal membrane protein that may be involved in the transport and metabolism of cobalamin. This protein also interacts with the large form of the hepatitis delta antigen and may be required for the nucleocytoplasmic shuttling of the hepatitis delta virus. Mutations in this gene are associated with the vitamin B12 metabolism disorder termed, homocystinuria-megaloblastic anemia complementation type F. [provided by RefSeq, Oct 2009]