Human Acetyl CoA synthetase (ACSS2) activation kit by CRISPRa

CAT#: GA111050

ACSS2 CRISPRa kit - CRISPR gene activation of human acyl-CoA synthetase short chain family member 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ACSS2
• Locus ID: 55902
• Kit Components:

  GA111050G1, ACSS2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA111050G2, ACSS2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA111050G3, ACSS2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001076552, NM_001242393, NM_018677, NM_139274, NR_028046
• Synonyms: ACAS2; ACECS; ACS; ACSA; dJ1161H23.1
• Summary: This gene encodes a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. The protein acts as a monomer and produces acetyl-CoA from acetate in a reaction that requires ATP. Expression of this gene is regulated by sterol regulatory element-binding proteins, transcription factors that activate genes required for the synthesis of cholesterol and unsaturated fatty acids. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009]