Human NKRF activation kit by CRISPRa

CAT#: GA111063

NKRF CRISPRa kit - CRISPR gene activation of human NFKB repressing factor

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NKRF
• Locus ID: 55922
• Kit Components:

  GA111063G1, NKRF gRNA vector 1 in pCas-Guide-CRISPRa

  GA111063G2, NKRF gRNA vector 2 in pCas-Guide-CRISPRa

  GA111063G3, NKRF gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001173487, NM_001173488, NM_017544
• Synonyms: ITBA4; NRF
• Summary: This gene encodes a transcriptional repressor that interacts with specific negative regulatory elements to mediate transcriptional repression of certain nuclear factor kappa B responsive genes. The protein localizes predominantly to the nucleolus with a small fraction found in the nucleoplasm and cytoplasm. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]