Human NSFL1C activation kit by CRISPRa

CAT#: GA111075

NSFL1C CRISPRa kit - CRISPR gene activation of human NSFL1 cofactor

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NSFL1C
• Locus ID: 55968
• Kit Components:

  GA111075G1, NSFL1C gRNA vector 1 in pCas-Guide-CRISPRa

  GA111075G2, NSFL1C gRNA vector 2 in pCas-Guide-CRISPRa

  GA111075G3, NSFL1C gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001206736, NM_016143, NM_018839, NM_182483, NR_038164
• Synonyms: dJ776F14.1; P47; UBX1; UBXD10; UBXN2C
• Summary: N-ethylmaleimide-sensitive factor (NSF) and valosin-containing protein (p97) are two ATPases known to be involved in transport vesicle/target membrane fusion and fusions between membrane compartments. A trimer of the protein encoded by this gene binds a hexamer of cytosolic p97 and is required for p97-mediated regrowth of Golgi cisternae from mitotic Golgi fragments. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 8. [provided by RefSeq, May 2011]