Human PDGFC activation kit by CRISPRa

CAT#: GA111090

PDGFC CRISPRa kit - CRISPR gene activation of human platelet derived growth factor C

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PDGFC
• Locus ID: 56034
• Kit Components:

  GA111090G1, PDGFC gRNA vector 1 in pCas-Guide-CRISPRa

  GA111090G2, PDGFC gRNA vector 2 in pCas-Guide-CRISPRa

  GA111090G3, PDGFC gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_016205, NR_036641
• Synonyms: FALLOTEIN; SCDGF
• Summary: The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a core motif of eight cysteines. This gene product appears to form only homodimers. It differs from the platelet-derived growth factor alpha and beta polypeptides in having an unusual N-terminal domain, the CUB domain. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2010]