Human CCBL2 (KYAT3) activation kit by CRISPRa

CAT#: GA111173

KYAT3 CRISPRa kit - CRISPR gene activation of human kynurenine aminotransferase 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: KYAT3
• Locus ID: 56267
• Kit Components:

  GA111173G1, KYAT3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA111173G2, KYAT3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA111173G3, KYAT3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001008661, NM_001008662, NM_001349447, NM_001349448, NM_001349449, NM_001349450, NR_146183, NR_146184, NR_146185
• Synonyms: CCBL2; KAT3; KATIII
• Summary: This gene encodes an aminotransferase that transaminates kynurenine to form kynurenic acid, which is a metabolite of tryptophan. Multiple alternatively spliced transcript variants that encode different proteins have been described for this gene. This gene shares 5' exon structure with the RNA binding motif protein, X-linked-like 1 locus on chromosome 1, but the coding sequences are non-overlapping. [provided by RefSeq, Mar 2017]