Human TRPV5 activation kit by CRISPRa

CAT#: GA111181

TRPV5 CRISPRa kit - CRISPR gene activation of human transient receptor potential cation channel subfamily V member 5

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TRPV5
• Locus ID: 56302
• Kit Components:

  GA111181G1, TRPV5 gRNA vector 1 in pCas-Guide-CRISPRa

  GA111181G2, TRPV5 gRNA vector 2 in pCas-Guide-CRISPRa

  GA111181G3, TRPV5 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_019841
• Synonyms: CAT2; ECAC1; OTRPC3
• Summary: This gene is a member of the transient receptor family and the TrpV subfamily. The calcium-selective channel encoded by this gene has 6 transmembrane-spanning domains, multiple potential phosphorylation sites, an N-linked glycosylation site, and 5 ANK repeats. This protein forms homotetramers or heterotetramers and is activated by a low internal calcium level. [provided by RefSeq, Jul 2008]