Human METTL3 activation kit by CRISPRa

CAT#: GA111183

METTL3 CRISPRa kit - CRISPR gene activation of human methyltransferase like 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: METTL3
• Locus ID: 56339
• Kit Components:

  GA111183G1, METTL3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA111183G2, METTL3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA111183G3, METTL3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_019852
• Synonyms: IME4; M6A; MT-A70; Spo8
• Summary: This gene encodes the 70 kDa subunit of MT-A which is part of N6-adenosine-methyltransferase. This enzyme is involved in the posttranscriptional methylation of internal adenosine residues in eukaryotic mRNAs, forming N6-methyladenosine. [provided by RefSeq, Jul 2008]