Human Leukotriene B4 Receptor 2 (LTB4R2) activation kit by CRISPRa
CAT#: GA111187
LTB4R2 CRISPRa kit - CRISPR gene activation of human leukotriene B4 receptor 2
Find the corresponding CRISPRi Inhibitor Kit
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 3gRNAs, 1 scramble ctrl and 1 enhancer vector |
Symbol | LTB4R2 |
Locus ID | 56413 |
Kit Components | GA111187G1, LTB4R2 gRNA vector 1 in pCas-Guide-CRISPRa GA111187G2, LTB4R2 gRNA vector 2 in pCas-Guide-CRISPRa GA111187G3, LTB4R2 gRNA vector 3 in pCas-Guide-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100058 |
Disclaimer | The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001164692, NM_001164693, NM_019839 |
Synonyms | BLT2; BLTR2; JULF2; KPG_004; LTB4-R 2; LTB4-R2; NOP9 |
Summary | Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTB4 > 12-epi-LTB4 > LTB5 > LTB3. [UniProtKB/Swiss-Prot Function] |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN414163 | LTB4R2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
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