Human TMPRSS4 activation kit by CRISPRa

CAT#: GA111204

TMPRSS4 CRISPRa kit - CRISPR gene activation of human transmembrane serine protease 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TMPRSS4
• Locus ID: 56649
• Kit Components:

  GA111204G1, TMPRSS4 gRNA vector 1 in pCas-Guide-CRISPRa

  GA111204G2, TMPRSS4 gRNA vector 2 in pCas-Guide-CRISPRa

  GA111204G3, TMPRSS4 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001083947, NM_001173551, NM_001173552, NM_001290094, NM_001290096, NM_019894, NM_183247, NR_110734
• Synonyms: CAPH2; MT-SP2; TMPRSS3
• Summary: This gene encodes a member of the serine protease family. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified as a gene overexpressed in pancreatic carcinoma. The encoded protein is membrane bound with a N-terminal anchor sequence and a glycosylated extracellular region containing the serine protease domain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]