Human KCNK13 activation kit by CRISPRa

CAT#: GA111211

KCNK13 CRISPRa kit - CRISPR gene activation of human potassium two pore domain channel subfamily K member 13

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: KCNK13
• Locus ID: 56659
• Kit Components:

  GA111211G1, KCNK13 gRNA vector 1 in pCas-Guide-CRISPRa

  GA111211G2, KCNK13 gRNA vector 2 in pCas-Guide-CRISPRa

  GA111211G3, KCNK13 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_022054
• Synonyms: K2p13.1; THIK-1; THIK1
• Summary: Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a potassium channel containing two pore-forming domains. This protein is an open channel that can be stimulated by arachidonic acid and inhibited by the anesthetic halothane. [provided by RefSeq, Jul 2013]