Human CTNNBIP1 activation kit by CRISPRa

CAT#: GA111329

CTNNBIP1 CRISPRa kit - CRISPR gene activation of human catenin beta interacting protein 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CTNNBIP1
• Locus ID: 56998
• Kit Components:

  GA111329G1, CTNNBIP1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA111329G2, CTNNBIP1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA111329G3, CTNNBIP1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001012329, NM_020248
• Synonyms: ICAT
• Summary: The protein encoded by this gene binds CTNNB1 and prevents interaction between CTNNB1 and TCF family members. The encoded protein is a negative regulator of the Wnt signaling pathway. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]