Human phospholipid scramblase 2 (PLSCR2) activation kit by CRISPRa

CAT#: GA111348

PLSCR2 CRISPRa kit - CRISPR gene activation of human phospholipid scramblase 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PLSCR2
• Locus ID: 57047
• Kit Components:

  GA111348G1, PLSCR2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA111348G2, PLSCR2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA111348G3, PLSCR2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001199978, NM_001199979, NM_020359
• Summary: This gene encodes a member of the phospholipid scramblase family. Phospholipid scramblases are membrane proteins that mediate calcium-dependent, non-specific movement of plasma membrane phospholipids and phosphatidylserine exposure. The encoded protein contains a low affinity calcium binding motif and may play a role in blood coagulation and apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]