Human DDX24 activation kit by CRISPRa

CAT#: GA111356

DDX24 CRISPRa kit - CRISPR gene activation of human DEAD-box helicase 24

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: DDX24
• Locus ID: 57062
• Kit Components:

  GA111356G1, DDX24 gRNA vector 1 in pCas-Guide-CRISPRa

  GA111356G2, DDX24 gRNA vector 2 in pCas-Guide-CRISPRa

  GA111356G3, DDX24 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_020414
• Synonyms: DEAD (Asp-Glu-Ala-Asp) box polypeptide 24; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 24; S. cerevisiae CHL1-like helicase
• Summary: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which shows little similarity to any of the other known human DEAD box proteins, but shows a high similarity to mouse Ddx24 at the amino acid level. [provided by RefSeq, Jul 2008]