Human CysLT2 (CYSLTR2) activation kit by CRISPRa

CAT#: GA111374

CYSLTR2 CRISPRa kit - CRISPR gene activation of human cysteinyl leukotriene receptor 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CYSLTR2
• Locus ID: 57105
• Kit Components:

  GA111374G1, CYSLTR2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA111374G2, CYSLTR2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA111374G3, CYSLTR2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001308465, NM_001308467, NM_001308468, NM_001308469, NM_001308470, NM_001308471, NM_001308476, NM_020377
• Synonyms: CYSLT2; CYSLT2R; GPCR21; HG57; hGPCR21; HPN321; KPG_011; PSEC0146
• Summary: The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, the protein encoded by this gene and CYSLTR1. This encoded receptor is a member of the superfamily of G protein-coupled receptors. It seems to play a major role in endocrine and cardiovascular systems. [provided by RefSeq, Jul 2008]