Human LYRM1 activation kit by CRISPRa

CAT#: GA111408

LYRM1 CRISPRa kit - CRISPR gene activation of human LYR motif containing 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: LYRM1
• Locus ID: 57149
• Kit Components:

  GA111408G1, LYRM1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA111408G2, LYRM1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA111408G3, LYRM1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001128301, NM_001128302, NM_001302835, NM_001302836, NM_020424, NR_126516, NR_126520, NR_126521, NR_126527, NR_126528, NM_001369632, NM_001369633, NM_001369635, NM_001369636, NM_001369638, NM_001369639, NM_001369641, NM_001369642, NM_001369644, NR_161425, NR_161426, NR_161429, NR_161430, NM_001369631, NM_001369634, NM_001369637, NM_001369645, NR_161427, NR_161431, NR_161432
• Synonyms: A211C6.1
• Summary: The protein encoded by this gene belongs to the mitochondrial leucine/tyrosine/arginine motif family of proteins. Proteins of this family are short polypeptides that contain a leucine/tyrosine/arginine motif near the N-terminus. This gene is widely expressed with high levels in omental adipose tissue of obese individuals. In adipose tissue, the protein is localized to the nucleus where it promotes preadipocyte proliferation and lowers the rate of apoptosis to regulate adipose tissue homeostasis. Overexpression of this gene in adipocytes causes abnormal mitochondrial morphology and mitochondrial dysfunction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]