Human SMURF1 activation kit by CRISPRa

CAT#: GA111413

SMURF1 CRISPRa kit - CRISPR gene activation of human SMAD specific E3 ubiquitin protein ligase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SMURF1
• Locus ID: 57154
• Kit Components:

  GA111413G1, SMURF1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA111413G2, SMURF1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA111413G3, SMURF1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001199847, NM_020429, NM_181349
• Synonyms: KIAA1625
• Summary: This gene encodes a ubiquitin ligase that is specific for receptor-regulated SMAD proteins in the bone morphogenetic protein (BMP) pathway. This protein plays a key roll in the regulation of cell motility, cell signalling, and cell polarity. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2010]