Human VARS2 activation kit by CRISPRa

CAT#: GA111427

VARS2 CRISPRa kit - CRISPR gene activation of human valyl-tRNA synthetase 2, mitochondrial

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: VARS2
• Locus ID: 57176
• Kit Components:

  GA111427G1, VARS2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA111427G2, VARS2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA111427G3, VARS2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001167733, NM_001167734, NM_020442
• Synonyms: COXPD20; VALRS; VARS2L; VARSL
• Summary: This gene encodes a mitochondrial aminoacyl-tRNA synthetase, which catalyzes the attachment of valine to tRNA(Val) for mitochondrial translation. Mutations in this gene cause combined oxidative phosphorylation deficiency-20, and are also associated with early-onset mitochondrial encephalopathies. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2014]