Human VANGL2 activation kit by CRISPRa

CAT#: GA111451

VANGL2 CRISPRa kit - CRISPR gene activation of human VANGL planar cell polarity protein 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: VANGL2
• Locus ID: 57216
• Kit Components:

  GA111451G1, VANGL2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA111451G2, VANGL2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA111451G3, VANGL2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_020335
• Synonyms: LPP1; LTAP; STB1; STBM; STBM1
• Summary: The protein encoded by this gene is a membrane protein involved in the regulation of planar cell polarity, especially in the stereociliary bundles of the cochlea. The encoded protein transmits directional signals to individual cells or groups of cells in epithelial sheets. This protein is also involved in the development of the neural plate. [provided by RefSeq, Sep 2011]