Human AICDA activation kit by CRISPRa

CAT#: GA111474

AICDA CRISPRa kit - CRISPR gene activation of human activation induced cytidine deaminase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: AICDA
• Locus ID: 57379
• Kit Components:

  GA111474G1, AICDA gRNA vector 1 in pCas-Guide-CRISPRa

  GA111474G2, AICDA gRNA vector 2 in pCas-Guide-CRISPRa

  GA111474G3, AICDA gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001330343, NM_020661
• Synonyms: AID; ARP2; CDA2; HEL-S-284; HIGM2
• Summary: This gene encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. The protein is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2). [provided by RefSeq, Feb 2009]