Human CYP20A1 activation kit by CRISPRa

CAT#: GA111481

CYP20A1 CRISPRa kit - CRISPR gene activation of human cytochrome P450 family 20 subfamily A member 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CYP20A1
• Locus ID: 57404
• Kit Components:

  GA111481G1, CYP20A1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA111481G2, CYP20A1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA111481G3, CYP20A1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_020674, NM_177538
• Synonyms: CYP-M; CYP-M, MGC22229; cytochrome P450 monooxygenase; cytochrome P450, family 20, subfamily A, polypeptide 1; MGC22229
• Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein lacks one amino acid of the conserved heme binding site. It also lacks the conserved I-helix motif AGX(D,E)T, suggesting that its substrate may carry its own oxygen. [provided by RefSeq, Jul 2008]