Human NMRAL1 activation kit by CRISPRa

CAT#: GA111484

NMRAL1 CRISPRa kit - CRISPR gene activation of human NmrA like redox sensor 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NMRAL1
• Locus ID: 57407
• Kit Components:

  GA111484G1, NMRAL1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA111484G2, NMRAL1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA111484G3, NMRAL1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001305141, NM_001305142, NM_020677, NM_001351994, NM_001351995, NM_001351996, NR_147845
• Synonyms: HSCARG; SDR48A1
• Summary: This gene encodes an NADPH sensor protein that preferentially binds to NADPH. The encoded protein also negatively regulates the activity of NF-kappaB in a ubiquitylation-dependent manner. It plays a key role in cellular antiviral response by negatively regulating the interferon response factor 3-mediated expression of interferon beta. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2015]