Human NLN activation kit by CRISPRa

CAT#: GA111529

NLN CRISPRa kit - CRISPR gene activation of human neurolysin

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NLN
• Locus ID: 57486
• Kit Components:

  GA111529G1, NLN gRNA vector 1 in pCas-Guide-CRISPRa

  GA111529G2, NLN gRNA vector 2 in pCas-Guide-CRISPRa

  GA111529G3, NLN gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_020726
• Synonyms: AGTBP; EP24.16; MEP; MOP
• Summary: This gene encodes a member of the metallopeptidase M3 protein family that cleaves neurotensin at the Pro10-Tyr11 bond, leading to the formation of neurotensin(1-10) and neurotensin(11-13). The encoded protein is likely involved in the termination of the neurotensinergic signal in the central nervous system and in the gastrointestinal tract. [provided by RefSeq, Jun 2010]