Human ARID1B activation kit by CRISPRa

CAT#: GA111533

ARID1B CRISPRa kit - CRISPR gene activation of human AT-rich interaction domain 1B

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ARID1B
• Locus ID: 57492
• Kit Components:

  GA111533G1, ARID1B gRNA vector 1 in pCas-Guide-CRISPRa

  GA111533G2, ARID1B gRNA vector 2 in pCas-Guide-CRISPRa

  GA111533G3, ARID1B gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_017519, NM_020732, NM_175863, NM_001346813, NM_001363725
• Synonyms: 6A3-5; BAF250B; BRIGHT; DAN15; ELD/OSA1; MRD12; OSA2; P250R
• Summary: This locus encodes an AT-rich DNA interacting domain-containing protein. The encoded protein is a component of the SWI/SNF chromatin remodeling complex and may play a role in cell-cycle activation. The protein encoded by this locus is similar to AT-rich interactive domain-containing protein 1A. These two proteins function as alternative, mutually exclusive ARID-subunits of the SWI/SNF complex. The associated complexes play opposing roles. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2016]