Human MYH7B activation kit by CRISPRa

CAT#: GA111654

MYH7B CRISPRa kit - CRISPR gene activation of human myosin heavy chain 7B

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MYH7B
• Locus ID: 57644
• Kit Components:

  GA111654G1, MYH7B gRNA vector 1 in pCas-Guide-CRISPRa

  GA111654G2, MYH7B gRNA vector 2 in pCas-Guide-CRISPRa

  GA111654G3, MYH7B gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_020884, NM_033424
• Synonyms: MHC14; MYH14
• Summary: The myosin II molecule is a multi-subunit complex consisting of two heavy chains and four light chains. This gene encodes a heavy chain of myosin II, which is a member of the motor-domain superfamily. The heavy chain includes a globular motor domain, which catalyzes ATP hydrolysis and interacts with actin, and a tail domain in which heptad repeat sequences promote dimerization by interacting to form a rod-like alpha-helical coiled coil. This heavy chain subunit is a slow-twitch myosin. Alternatively spliced transcript variants have been found, but the full-length nature of these variants is not determined. [provided by RefSeq, Mar 2010]