Human PLEKHA4 activation kit by CRISPRa

CAT#: GA111669

PLEKHA4 CRISPRa kit - CRISPR gene activation of human pleckstrin homology domain containing A4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PLEKHA4
• Locus ID: 57664
• Kit Components:

  GA111669G1, PLEKHA4 gRNA vector 1 in pCas-Guide-CRISPRa

  GA111669G2, PLEKHA4 gRNA vector 2 in pCas-Guide-CRISPRa

  GA111669G3, PLEKHA4 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001161354, NM_020904
• Synonyms: PEPP1
• Summary: This gene encodes a pleckstrin homology (PH) domain-containing protein. The PH domain is found near the N-terminus and contains a putative phosphatidylinositol 3, 4, 5-triphosphate-binding motif (PPBM). Elevated expression of this gene has been observed in some melanomas. Alternate splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2017]