Human MAGEE1 activation kit by CRISPRa

CAT#: GA111688

MAGEE1 CRISPRa kit - CRISPR gene activation of human MAGE family member E1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MAGEE1
• Locus ID: 57692
• Kit Components:

  GA111688G1, MAGEE1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA111688G2, MAGEE1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA111688G3, MAGEE1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_020932
• Synonyms: DAMAGE; HCA1
• Summary: This gene encodes an alpha-dystrobrevin-associated MAGE (melanoma-associated antigen) protein, which is a member of the MAGE family. The protein contains a nuclear localization signal in the N-terminus, 30 12-amino acid repeats beginning at nt 60 with the consensus sequence ASEGPSTSVLPT, and two MAGE domains in the C-terminus. It may play a signaling role in brain, muscle, and peripheral nerve. This gene is located on X chromosome in a region containing loci linked to cognitive disability. [provided by RefSeq, Mar 2010]