Human CTDSP1 activation kit by CRISPRa

CAT#: GA111758

CTDSP1 CRISPRa kit - CRISPR gene activation of human CTD small phosphatase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CTDSP1
• Locus ID: 58190
• Kit Components:

  GA111758G1, CTDSP1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA111758G2, CTDSP1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA111758G3, CTDSP1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001206878, NM_001206879, NM_021198, NM_182642
• Synonyms: NIF3; NLI-IF; NLIIF; SCP1
• Summary: This gene encodes a member of the small C-terminal domain phosphatase (SCP) family of nuclear phosphatases. These proteins play a role in transcriptional regulation through specific dephosphorylation of phosphoserine 5 within tandem heptapeptide repeats of the C-terminal domain of RNA polymerase II. The encoded protein plays a role in neuronal gene silencing in non-neuronal cells, and may also inhibit osteoblast differentiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]