Human PRUNE (PRUNE1) activation kit by CRISPRa

CAT#: GA111780

PRUNE1 CRISPRa kit - CRISPR gene activation of human prune exopolyphosphatase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PRUNE1
• Locus ID: 58497
• Kit Components:

  GA111780G1, PRUNE1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA111780G2, PRUNE1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA111780G3, PRUNE1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001303229, NM_001303242, NM_001303243, NM_021222, NR_130130, NR_130131, NR_130132, NR_130135
• Synonyms: DRES-17; DRES17; HTCD37
• Summary: This gene encodes a member of the DHH protein superfamily of phosphoesterases. This protein has been found to function as both a nucleotide phosphodiesterase and an exopolyphosphatase. This protein is believed to stimulate cancer progression and metastases through the induction of cell motility. A pseuodgene has been identified on chromosome 13. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]