Human HRH4 activation kit by CRISPRa

CAT#: GA111826

HRH4 CRISPRa kit - CRISPR gene activation of human histamine receptor H4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: HRH4
• Locus ID: 59340
• Kit Components:

  GA111826G1, HRH4 gRNA vector 1 in pCas-Guide-CRISPRa

  GA111826G2, HRH4 gRNA vector 2 in pCas-Guide-CRISPRa

  GA111826G3, HRH4 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001143828, NM_001160166, NM_021624
• Synonyms: AXOR35; BG26; GPCR105; GPRv53; H4; H4R; HH4R
• Summary: Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by a family of histamine receptors, which are a subset of the G-protein coupled receptor superfamily. This gene encodes a histamine receptor that is predominantly expressed in haematopoietic cells. The protein is thought to play a role in inflammation and allergy reponses. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]