Human LGR7 (RXFP1) activation kit by CRISPRa

CAT#: GA111834

RXFP1 CRISPRa kit - CRISPR gene activation of human relaxin family peptide receptor 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RXFP1
• Locus ID: 59350
• Kit Components:

  GA111834G1, RXFP1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA111834G2, RXFP1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA111834G3, RXFP1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001253727, NM_001253728, NM_001253729, NM_001253730, NM_001253732, NM_001253733, NM_021634, NR_045579, NR_045580, NR_045581, NR_045582, NR_045583, NR_045584, NM_001363776
• Synonyms: LGR7; RXFPR1
• Summary: This gene encodes a member of the leucine-rich repeat-containing subgroup of the G protein-coupled 7-transmembrane receptor superfamily. The encoded protein plays a critical role in sperm motility, pregnancy and parturition as a receptor for the protein hormone relaxin. Decreased expression of this gene may play a role in endometriosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]