Human KIF13A activation kit by CRISPRa

CAT#: GA111939

KIF13A CRISPRa kit - CRISPR gene activation of human kinesin family member 13A

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: KIF13A
• Locus ID: 63971
• Kit Components:

  GA111939G1, KIF13A gRNA vector 1 in pCas-Guide-CRISPRa

  GA111939G2, KIF13A gRNA vector 2 in pCas-Guide-CRISPRa

  GA111939G3, KIF13A gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001105566, NM_001105567, NM_001105568, NM_001243423, NM_022113
• Synonyms: bA500C11.2; RBKIN
• Summary: This gene encodes a member of the kinesin family of microtubule-based motor proteins that function in the positioning of endosomes. This family member can direct mannose-6-phosphate receptor-containing vesicles from the trans-Golgi network to the plasma membrane, and it is necessary for the steady-state distribution of late endosomes/lysosomes. It is also required for the translocation of FYVE-CENT and TTC19 from the centrosome to the midbody during cytokinesis, and it plays a role in melanosome maturation. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011]