Human Neurogenin 2 (NEUROG2) activation kit by CRISPRa

CAT#: GA111940

NEUROG2 CRISPRa kit - CRISPR gene activation of human neurogenin 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NEUROG2
• Locus ID: 63973
• Kit Components:

  GA111940G1, NEUROG2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA111940G2, NEUROG2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA111940G3, NEUROG2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_024019
• Synonyms: Atoh4; bHLHa8; Math4A; ngn-2; NGN2
• Summary: This gene encodes a neural-specific basic helix-loop-helix (bHLH) transcription factor that can specify a neuronal fate on ectodermal cells and is expressed in neural progenitor cells within the developing central and peripheral nervous systems. The protein product of this gene also plays a role in the differentiation and survival of midbrain dopaminergic neurons. [provided by RefSeq, Apr 2012]