Human XYLT1 activation kit by CRISPRa

CAT#: GA111993

XYLT1 CRISPRa kit - CRISPR gene activation of human xylosyltransferase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: XYLT1
• Locus ID: 64131
• Kit Components:

  GA111993G1, XYLT1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA111993G2, XYLT1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA111993G3, XYLT1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_022166
• Synonyms: DBQD2; PXYLT1; XT-I; XT1; XTI; xylT-I; XYLTI
• Summary: This locus encodes a xylosyltransferase enzyme. The encoded protein catalyzes transfer of UDP-xylose to serine residues of an acceptor protein substrate. This transfer reaction is necessary for biosynthesis of glycosaminoglycan chains. Mutations in this gene have been associated with increased severity of pseudoxanthoma elasticum. [provided by RefSeq, Nov 2009]