Human ABCG4 activation kit by CRISPRa

CAT#: GA111996

ABCG4 CRISPRa kit - CRISPR gene activation of human ATP binding cassette subfamily G member 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ABCG4
• Locus ID: 64137
• Kit Components:

  GA111996G1, ABCG4 gRNA vector 1 in pCas-Guide-CRISPRa

  GA111996G2, ABCG4 gRNA vector 2 in pCas-Guide-CRISPRa

  GA111996G3, ABCG4 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001142505, NM_022169, NM_001348191, NM_001348192
• Synonyms: WHITE2
• Summary: The protein encoded by this gene is a member of the ATP-binding cassette (ABC) transporter superfamily. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). The encoded protein is a member of the White subfamily and plays an important role in cellular cholesterol homeostasis. This protein functions as either a homodimer or as a heterodimer with another ABC subfamily protein such as ABCG1. [provided by RefSeq, Jan 2017]