Human Apg3 (ATG3) activation kit by CRISPRa

CAT#: GA112073

ATG3 CRISPRa kit - CRISPR gene activation of human autophagy related 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ATG3
• Locus ID: 64422
• Kit Components:

  GA112073G1, ATG3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA112073G2, ATG3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA112073G3, ATG3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001278712, NM_022488
• Synonyms: APG3; APG3-LIKE; APG3L; PC3-96
• Summary: This gene encodes a ubiquitin-like-conjugating enzyme and is a component of ubiquitination-like systems involved in autophagy, the process of degradation, turnover and recycling of cytoplasmic constituents in eukaryotic cells. This protein is known to play a role in regulation of autophagy during cell death. A pseudogene of this gene is located on chromosome 20. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]