Human C14orf151 (INF2) activation kit by CRISPRa

CAT#: GA112074

INF2 CRISPRa kit - CRISPR gene activation of human inverted formin, FH2 and WH2 domain containing

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: INF2
• Locus ID: 64423
• Kit Components:

  GA112074G1, INF2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA112074G2, INF2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA112074G3, INF2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001031714, NM_022489, NM_032714
• Synonyms: C14orf151; C14orf173; CMTDIE; FSGS5; pp9484
• Summary: This gene represents a member of the formin family of proteins. It is considered a diaphanous formin due to the presence of a diaphanous inhibitory domain located at the N-terminus of the encoded protein. Studies of a similar mouse protein indicate that the protein encoded by this locus may function in polymerization and depolymerization of actin filaments. Mutations at this locus have been associated with focal segmental glomerulosclerosis 5. [provided by RefSeq, Aug 2010]